Best Vitamin B12 Supplements of 2025 • Sotaku (2025)

• Energy metabolism: This means that vitamin B12 is used to help convert food into energy.
• Blood cell formation: Vitamin B12 is needed to make red blood cells. These carry oxygen to the body’s tissues, where it is used to produce energy. This key vitamin also plays a role in the immune system.
• Nerve function: Vitamin B12 is also needed for the proper function of the nervous system. It helps to maintain nerve cells which are required to produce energy and communicate with each other.
• DNA synthesis: Vitamin B12 is also involved in DNA synthesis, the process by which DNA is created and repaired.

Vitamin B12 plays a significant role in maintaining our wellbeing and may benefit a wide range of people.

Despite its importance, some people may struggle to consume sufficient amounts of B12-rich foods each day and choose to turn to B12 supplements.

• People who mostly follow a plant-based diet: Vitamin B12 is naturally found in animal products, so people who are vegan, vegetarian, or mostly follow a plant-based diet may not get enough vitamin B12 from their diet.
• People over the age of 50: The risk of low vitamin B12 increases with age.
• People with certain conditions: Some health issues may interfere with the body’s ability to absorb vitamin B12.

• Tablets: Easy to swallow and can be taken with or without food.
• Capsules: Similar to tablets, but encased in a capsule which may make them easier to swallow for some people.
• Gummies: Chewable supplements that may sometimes contain sugar or syrup amongst other additional ingredients.
• Liquid: Available as drops or sprays.
• Multivitamins: Quality multivitamins often contain vitamin B12 amongst other essential vitamins and minerals.

• Convenience: Multivitamins offer a convenient way to get your daily dose of vitamin B12. They are easy to take and you only need to take one capsule per day.
• Price: Multivitamins are relatively affordable, especially compared to some other forms of vitamin B12 supplements.
• Other essential nutrients: Multivitamins often contain other essential nutrients, such as folate, magnesium, calcium, and vitamin D. This can be helpful if you are not getting enough of these through diet alone.*

• Methylcobalamin: The type of vitamin B12 in a multivitamin is important because some forms are thought to be more bioavailable than others. Methylcobalamin is thought to be more bioavailable than cyanocobalamin (bioavailability refers to how well a nutrient is absorbed by the body).*
• Amount of vitamin B12: The amount of vitamin B12 varies from supplement to supplement. Consult with your doctor to help select the right amount for your individual needs.
• Ease of use: You are more likely to be consistent with a supplement that best suits your lifestyle, needs, and personal preferences.
• Other nutrients: If you are considering vitamin stacking, check the multivitamin label to determine which nutrients it contains.

• Cyanocobalamin: This is a synthetic type of vitamin B12. Although it’s commonly used, it’s thought to be less bioavailable than methylcobalamin.*
• Unclear labels: All high-quality supplements should clearly list exactly what’s included in the formula. Avoid products lacking transparency that don't clearly state the type of vitamin B12 contained in the B12 supplement.
• Missing safety testing & certifications: Choose a supplement that has been independently third-party lab tested. These precautions will guarantee that the product is top quality and free from unwanted extras, such as contaminants, traces of heavy metals, or pesticides.
• Choosing according to price: When it comes to your health, this is definitely not an area to test out suspiciously cheap products. Before you’re tempted to go for the cheapest option, keep in mind that there are plentiful options to choose from that are high value and still affordable.

• Vitamin B12 as methylcobalamin
• Includes 20 other vitamins and minerals including D3, C, and folate
• Contains zinc, magnesium, and selenium
• Includes citrus bioflavonoids plus the antioxidants lutein and lycopene
• 1 capsule a day
• Made in the USA with globally sourced ingredients
• 90-day money-back guarantee
• Third-party lab tested
• Subscribe & Save program

• Only available online
• Due to popularity, sometimes runs out of stock

Primal Multivitamin by Primal Harvest is a multivitamin that combines vitamin B12, in the form of methylcobalamin, with a wide spectrum of other body-ready vitamins and minerals. Its premium vitamin-mineral blend includes folate, vitamin D, magnesium, essential B vitamins, selenium, zinc, manganese, calcium and more. What makes this multivitamin unique is that it also features lutein, lycopene, and citrus bioflavonoid complex for added antioxidant properties. This multivitamin takes a comprehensive approach to supporting overall wellness and helping to fill nutritional gaps with its premium, easy-to-swallow once-daily capsules.*

Primal Harvest’s Primal Multivitamin is third-party lab tested and is made in the USA with globally sourced ingredients. The brand has a convenient Subscribe & Save program which means you can order this formula through their convenient and hassle-free subscription service. By signing up for a subscription you get 20% off all products plus free shipping. The brand also offers great deals if you purchase multiple bottles at once. To top it off, Primal Harvest offers a 90-day money-back guarantee on all of their products.

• Vitamin B12 as methylcobalamin
• Once-daily capsule
• Price

• No other vitamins or minerals
• 60-day money-back guarantee

Vitamin B12 by Nutricost is a once-daily vitamin B12 capsule that includes ,000 mcg of vitamin B12. Each bottle contains 240 capsules, making it an affordable option. However, some may want to note that the formula only contains vitamin B12, so those interested in combining vitamin B12 with other nutrients would need to supplement these capsules with other products.

Additionally, the brand has a slightly shorter returns policy than some of the others featured on this list.

• Vitamin B12 as methylcobalamin
• Once-daily capsule
• Includes probiotics

• No other vitamins or minerals
• Contains milk and soy
• 30-day money-back guarantee

Bio-Kult Boosted by Bio-Kult is a probiotic formula that includes vitamin B12. Although the formula contains a comprehensive range of probiotics, it does not contain other vitamins or minerals like folate. It comes in capsule form which should be taken once daily. Those with certain allergen concerns may want to note that the product contains milk and soy.

Other considerations include the 30-day returns policy and the fact that there is no information available on the website that confirms whether the product has been third-party tested.

• Vitamin B12 as methylcobalamin
• Includes folate and vitamin B6
• Once-daily tablet

• No minerals
• Can only be purchased through a third-party retailer

Vitamin B12 1,000 mcg by Vispura is a B12 tablet that also includes vitamin B6 and folic acid. This formula delivers vitamin B12 in the form of methylcobalamin but doesn’t include any minerals or other vitamins than the ones mentioned above. It comes in a bottle of 180 tablets and has a serving of one capsule per day.

Some may want to note that it can only be purchased in the US through a third-party retailer which means that the returns policy may differ according to the retailer’s policies.

• With 500 mcg vitamin B12
• Once-daily tablet
• Includes calcium
• Subscribe & Save program

• Vitamin B12 as cyanocobalamin
• No other vitamins or minerals
• 30-day returns policy

Nature Made Vitamin B12 is combined with calcium and delivered in a tablet that should be taken once per day. Although the formula also includes the mineral calcium, it doesn’t contain any other vitamins or minerals. One thing to note is that although the formula provides B12, it does so in the form of cyanocobalamin rather than methylcobalamin like many of the other products featured here.

Additionally, some may want to note the 30-day returns policy.

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*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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